R is a programming language and software environment used for statistical analysis, data modeling, graphical representation and reporting. R is best tool for software programmers, statisticians and data miners who looking forward for to easily manipulate and present data in compelling ways. R has gained wide acceptance as a reliable and powerful modern computational environment for statistical computing and visualisation, and is now used in many areas of scientific computation. One of the main reasons that computational biologists use R is the Bioconductor project (http://www.bioconductor.org), which is a set of packages for R to analyse genomic data. These packages have, in many cases, been provided by researchers to complement descriptions of algorithms in journal articles. Many computational biologists regard R and Bioconductor as fundamental tools for their research.